Dermoscopy of Hair and Scalp Disorders

 Dermoscopy has been increasing in popularity as a diagnostic investigational method, but the skin containing hair poses rather different problems from the skin on the rest od the body. This pioneering text examines the different conditions that can be investigated and sets out the results that can be obtained. 
with over 230 colour illustrations. 

Di prossima pubblicazione per Pioda Imaging Edizioni. 

Medicina Estetica - Tricologia - PapersRSS

Anagen Effluvium Caused by Thallium Poisoning

Anagen effluvium is the abrupt loss of hair during the growth phase due to an insult that impairs mitotic or metabolic activity of the hair follicle. This form of hair loss is essentially synonymous with chemotherapy-induced alopecia. Less common causes include medications, radiation, toxic chemicals, andinflammatory disease. Thallium, once considered the “poisoner’spoison,” is anodorless, flavorless, colorless heavy metal and a rare cause of anagen effluvium.



Androgenetic alopecia: a review

Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism of androgenetic alopecia. Methods Using the PubMed database, we conducted a systematic review of the literature, selecting studies published from 1916 to 2016. Results The occurrence and development of androgenetic alopecia depends on the interaction of endocrine factors and genetic predisposition. Androgenetic alopecia is characterized by progressive hair follicular miniaturization, caused by the actions of androgens on the epithelial cells of genetically susceptible hair follicles in androgen-dependent areas. Although the exact pathogenesis of androgenetic alopecia remains to be clarified, research has shown that it is a polygenetic condition. Numerous studies have unequivocally identified two major genetic risk loci for androgen ...



Hair restoration surgery: challenges and solutions

Hair loss is a common problem affecting both men and women. The most frequent etiology is androgenetic alopecia, but other causes of hair loss such as trauma, various dermatologic diseases, and systemic diseases can cause alopecia. The loss of hair can have profound effects on one’s self esteem and emotional well-being, as one’s appearance plays a role in the work place and interpersonal relationships. It is therefore not surprising that means to remedy hair loss are widely sought. Hair transplant surgery has become increasingly popular, and the results that we are able to create today are quite remarkable, providing a natural appearance when the procedure is performed well. In spite of this, hair transplant surgery is not perfect. It is not perfect because the hair transplant surgeon is still faced with challenges that prevent the achievement of optimal results. Some of these challenges include a limit to donor hair availability, hair survival, and ways to conceal any evidence of a su ...



Platelet-rich plasma for androgenetic alopecia: Does it work? Evidence from meta analysis

The use of platelet-rich plasma (PRP) has increased among different surgical specialities for the treatment of various conditions. Androgenetic alopecia is a common condition, with severe attendant psychosocial implications. PRP injections for hair restoration have become a popular practice among plastic surgeons. We performed a meta-analysis comparing local injection of platelet-rich plasma versus control to evaluate this issue in order to investigate the effectiveness of PRP local injections for androgenetic alopecia.



Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signaling pathways

Male androgenetic alopecia (AGA) is the most common form of hair loss in men and is characterized by a distinct pattern of progressive hair loss starting from the frontal area and the vertex of the scalp. Although several genetic risk loci have been identified, relevant genes for AGA remain to be defined.



The importance of trichological examination in the diagnosis of alopecia areata

In this article we discuss the propedeutic aspects of alopecia areata, especially those found by dermatoscopy, an invaluable tool for diagnosis of the condition. Dermatoscopy facilitates the early detection of the characteristic changes in alopecia areata hair such as exclamation-point hairs, cadaverous hair, fuzzy hair, vellus type hair and yellow spots.



Direttore di collana: Michele Pascali

Dal settembre 2012 ad oggi ricopre la qualifica di Dirigente Medico I° livello presso l’U.O.C di Chirurgia Plastica-Ricostruttiva ed Estetica dell’Università di Roma “Tor Vergata”.
Dal 2013 ad oggi Docente e Coordinatore Didattico del Master Universitario II Livello in Chirurgia Plastica ed Estetica del Distretto Facciale dell’Università di Roma “Tor Vergata”.
Docente presso la Scuola di Specializzazione in Chirurgia Plastica-Ricostruttiva ed Estetica dell’Università di Roma “Tor Vergata”.
Dal settembre 2013 ad oggi ricopre la qualifica di Consulente di Chirurgia Plastica presso il Ministero dell’Interno.
Dal 2014 ad oggi coordinatore scientifico del Corso Avanzato di Dissezione Anatomica e Tecniche Chirurgiche del Distretto Facciale”, presso l’ICLO Teaching and Research Center San Francesco di Sales, Arezzo.
Dal 2017 Professore a contratto di Plastic Surgery  Corso di Laurea in Medicine and Surgery Università di Roma “Tor Vergata”."

Da dicembre 2013 dirige il Centro Chirurgia Estetica Dalmazia di via Novara In Roma.




 Membro effettivo delle seguenti Società:

SICPRE - Società Italiana di Chirurgia Plastica Ricostruttiva ed Estetica
EAFPS - European Academy of Facial Plastic Surgery
AICEF - Associazione Italiana ORL di Chirurgia Estetica e Funzionale Rino-Cervico-Facciale
ACPIC - Associazione dei Chirurghi Plastici dell'Italia Centrale
SIMCRI- Società Italiana di Medicina e Chirurgia Rigenerativa 


20 luglio 199: Si è laureato in Medicina e Chirurgia presso l’Università  degli Studi di Roma “La Sapienza” con voto di 110/110 lode

3 agosto 2012: 
Si è specializzato in Chirurgia Plastica -Ricostruttiva  ed Estetica con il voto di 50/50 e LODE presso l’Università degli Studi di Roma  “Tor Vergata”, discutendo una tesi sperimentale dal titolo “Midface lifting: nuove tendenze nella chirurgia estetica del volto”

9 marzo 2016: Ha conseguito il Dottorato di ricerca in “Chirurgia Rigenerativa” dell’Università di Roma “Tor Vergata” discutendo una tesi dal titolo “Utilizzo del Lipostructure e PRP nel ripristino dei volumi del volto”


  • Vertical Midface Lifting with Periorbital Anchoring in the Management of Lower Eyelid Retraction: A Ten-Year Clinical Retrospective Study. 
    Pascali M, Botti C, Cervelli V, Botti G. Plast Reconstr Surg, 2017 In print.
  • Midface –lift patient  satisfaction: A 5-year follow-up study Pascali M, Quarato D, Bocchini I, Cervelli V.  Indian Journal of Plastic Surgery 2016 Dec ;49(3):329. 
  • Dome Division: A Viable Technique Today?  Boccieri A, Sciuto S, Cervelli V, Pascali M. Facial Plast Surg. 2016 Dec;32(6):664-670.
  • Treatment of the Crooked Nose: The Final Steps to Perfection.  Pascali M, Boccieri A, Carinci F, Cervelli V. J Craniofac Surg. 2016 Dec 23
  • Tarsal Strip Versus Tarsal Belt in Ectropion Correction: A Statistical Evaluation.  Pascali M, Avantaggiato A, Carinci F.  J Craniofac Surg. 2016 Oct 14. [Epub ahead of print]
  • Reshaping of the Anterior Nasal Spine: An Important Step in Rhinoplasty. Marianetti TM, Boccieri A, Pascali M. Plast Reconstr Surg Glob Open. 2016 Sep 23;4(9):e1026
  • Non-ablative radio-frequency rejuvenation: a histological and bio-molecular report. Avantaggiato A, Andreasi Bassi M, Cura F, Pascali M, Carinci F. J Biol Regul Homeost Agents. 2016 Apr-Jun;30(2 Suppl 1):223-30. 
  • Brows Asymmetry Correction With the Direct Approach: Myth or Reality? Pascali M, Carinci F, Bocchini I, Avantaggiato A, Cervelli V.  J Craniofac Surg. 2016 Mar;27(2):365-9.
  • The Auricular Cartilage in 197 Secondary and Tertiary Rhinoplasties.  Pascali M, Gentile P, Di Pasquali C, Bocchini I, Cervelli V. J Craniofac Surg. 2016 Mar;27(2):339-44.
  • Direct brow lifting: Specific indications for a simplified approach to eyebrow ptosis.  Pascali M, Bocchini I, Avantaggiato A, Carinci F, Cervelli V, Orlandi F, Quarato D.  Indian Journal of Plastic Surgery 2016 Jan;49(1):66.
  • The theories of aging: reactive oxygen species and what else? Avantaggiato A, Bertuzzi G, Pascali M, Candotto V, Carinci F. J Biol Regul Homeost Agents. 2015 Jul-Sep;29(3 Suppl 1):156-63.
  • Hyaluronic acid in dermal rejuvenation: an in vitro study. Avantaggiato A, Pascali M, Lauritano D, Cura F, Pezzetti F, Palmieri A. J Biol Regul Homeost Agents. 2015 Jul-Sep;29(3 Suppl 1):149-55.
  • Reconstruction of the zygomatic bone with smartbone®: case report.  Grecchi F, Perale G, Candotto V, Busato A, Pascali M, Carinci F. J Biol Regul Homeost Agents. 2015 Jul-Sep;29(3 Suppl 1):42-7.
  • Hyaluronic acid: the use of its precursor in skin bio-stimulation. Avantaggiato A, Martinelli M, Palmieri A, Pascali M, Bertuzzi G, Carinci F. J Biol Regul Homeost Agents. 2015 Jul-Sep;29(3):647-54.
  • Reply: Midface Rejuvenation: A Critical Evaluation of a 7-Year Experience.  Pascali M, Botti C, Cervelli V, Botti G. Plast Reconstr Surg. 2015 Dec;136(6):840e-2e
  • Bio-Revitalization: Effects of NASHA on Genes Involving Tissue Remodeling. Avantaggiato A, Girardi A, Palmieri A, Pascali M, Carinci F. Aesthetic Plast Surg. 2015 Aug;39(4):459-64.
  • Lateral Canthal Support in Prevention of Lower Eyelid Malpositioning in Blepharoplasty: The Tarsal Sling. Pascali M, Avantaggiato A, Brinci L, Cervelli V, Carinci F. J Craniofac Surg. 2015 Jun;26(4):e339-42.
  • Comparison among three different fixation techniques in temporal brow lift surgery.  Pascali M, Avantaggiato A, Bocchini I, Carinci F, Cervelli V. J Craniofac Surg. 2015 May;26(3):906-10.
  • Midface rejuvenation: a critical evaluation of a 7-year experience. Pascali M, Botti C, Cervelli V, Botti G. Plast Reconstr Surg. 2015 May;135(5):1305-16.
  • Comparison of Bio-Revitalizing Injective Products: A Study on Skin Fibroblast Cultures. Avantaggiato A, Girardi A, Palmieri A, Pascali M, Carinci F. Rejuvenation Res. 2015 Jun;18(3):270-6.
  • Tarsal sling: an essential stitch to prevent scleral show in lower blepharoplasty. Pascali M, Avantaggiato A, Brinci L, Cervelli V, Carinci F. Aesthet Surg J. 2015 Jan;35(1):11-9.
  • Role of antioxidants in dermal aging: an in vitro study by q-RT-PCR. Avantaggiato A, Bertuzzi G, Vitiello U, Iannucci G, Pasin M, Pascali M, Cervelli V, Carinci F.  Aesthetic Plast Surg. 2014 Oct;38(5):1011-6.
  • Our Experience with Brow Ptosis Correction: A Comparison of 4  Techniques.  Pascali M, Bocchini I, Avantaggiato A Carinci F, Cervelli V Plast Reconstr Surg Glob Open. 2015 Mar; 3(3): e337.
  • The tarsal belt procedure for the correction of ectropion: description and outcome in 42 cases. Pascali M, Corsi A, Brinci L, Corsi I, Cervelli V.  Br J Ophthalmol. 2014 Dec;98(12):1691-6.
  • Adipose-derived stromal vascular fraction cells and platelet-rich plasma: basic and clinical evaluation for cell-based therapies in patients with scars on the face. Gentile P, De Angelis B, Pasin M, Cervelli G, Curcio CB, Floris M, Di Pasquali C, Bocchini I, Balzani A, Nicoli F, Insalaco C, Tati E, Lucarini L, Palla L, Pascali M, De Logu P, Di Segni C, Bottini DJ, Cervelli V. J Craniofac Surg. 2014 Jan;25(1):267-72. 
  • Comparison of commercial fibrin sealants in facelift surgery: a prospective study. Botti G, Pascali M, Botti C, Bodog F, Gentile P, Cervelli V. Clin Cosmet Investig Dermatol. 2013 Nov 7;6:273-80.
  • Medial thighplasty: horizontal and vertical procedures after massive weight loss. Labardi L, Gentile P, Gigliotti S, Marianetti M, Colicchia GM, Pascali M, Brinci L, Cervelli V. J Cutan Aesthet Surg. 2012 Jan;5(1):20-5.
  • A clinical trial in facial fat grafting: filtered and washed versus centrifuged fat. Botti G, Pascali M, Botti C, Bodog F, Cervelli V. Plast Reconstr Surg. 2011 Jun;127(6):2464-73.
  • An original application of the Endotine Ribbon device for brow lift. Pascali M, Gualdi A, Bottini DJ, Botti C, Botti G, Cervelli V. Plast Reconstr Surg. 2009 Nov;124(5):1652-61.
  • Autologous platelet-rich plasma mixed with purified fat graft in aesthetic plastic surgery. Cervelli V, Palla L, Pascali M, De Angelis B, Curcio BC, Gentile P. Aesthetic Plast Surg. 2009 Sep;33(5):716-21.
  • Alar batten cartilage graft: treatment of internal and external nasal valve collapse. Cervelli V, Spallone D, Bottini JD, Silvi E, Gentile P, Curcio B, Pascali M. Aesthetic Plast Surg. 2009 Jul;33(4):625-34.
  • The use of spreader grafts in primary rhinoplasty.  Boccieri A, Macro C, Pascali M. Ann Plast Surg. 2005 Aug;55(2):127-31.
  • The atraumatic septhorinoplasty. Boccieri A., Pascali M., Macro C. Eur J Plast Surg. 2005 28: 343-353
  • Septal crossbar graft for the correction of the crooked nose. Boccieri A, Pascali M. Plast Reconstr Surg. 2003 Feb;111(2):629-38.
  • Surgical treatment of frontoethmoidal encephalocele: a case report. De Ponte FS, Pascali M, Perugini M, Lattanzi A, Gennaro P, Brunelli A. J Craniofac Surg. 2000 Jul;11(4):342-5.
  • Obstructive sleep apnea in a growing patient. De Ponte F, Sassano P, Gennaro P, Pascali M, Marchetti E. J Craniofac Surg. 1999 Sep;10(5):430-4.

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